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Interactions between a nutrient and a drug may occur in either of two ways: a nutrient may alter the pharmacokinetics and/or pharmacodynamics of a drug (nutrient–drug interaction) or a drug may alter the concentration and/or biological activity of a nutrient in the organism (drug–nutrient interaction) ( Reference Chan 24 )

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Consensus sequence One approach that has been taken is to design vaccine antigens that are enriched for conserved T and B-cell epitopes either as a consensus sequence (which is the closest natural circulating sequence to a bioinformatically calculated consensus) or as a string of epitopes taken out of their natural context within the viral protein (Fig